Designator

OpenAI’s Head of ChatGPT: We’re entering a new era of AI (again) | Tibo Sottiaux

OpenAI's head of ChatGPT, Tibo Sottiaux, discusses the future of AI, predicting that agents will soon perform most internet actions and highlighting the increasing value of human skills.

4 Oct37 min listen/watch

14 Sept51 min listen/watch

Greg Brockman on Why OpenAI Says We’re Entering the AGI Era

OpenAI's president believes AI has entered a new phase, with models capable of 24-hour coherent work and human-like software interaction, potentially leading to artificial general intelligence.

6 Sept79 min listen/watch

Why companies are becoming a series of loops | Anish Acharya (a16z)

Andreessen Horowitz General Partner Anish Acharya suggests that successful company building now involves creating a series of loops, emphasizing distribution as a crucial, discovered moat in the AI era.

30 Aug82 min listen/watch

AI’s third era: the rise of persistent AI coworkers | Tara Seshan (OpenAI’s product lead)

OpenAI's product lead discusses the shift from "rowing" to "steering" as AI agents become coworkers, emphasizing human judgment and ambition as key differentiators in the evolving product management role.

23 Aug85 min listen/watch

How to close $100K+ enterprise deals, step by step | Jen Abel

Jen Abel outlines a 15-step enterprise sales cycle, contrasting it with the typical five-stage CRM pipeline, covering everything from landing the first meeting to navigating procurement and securing a signature.

16 Aug72 min listen/watch

OpenAI’s Head of Design: This is the best time in history to be a designer | Ian Silber

OpenAI's Head of Design, Ian Silber, discusses why this era is optimal for product designers, how AI impacts design teams, and what OpenAI seeks in design hires.

Syntax

12 Aug60 min listen/watch

1029: The Workflow of the Future With Zed

Developers discuss Zed, a tool built in Rust, and its new version control system DeltaDB.

12 Aug52 min listen/watch

Garry Tan on Taste, Agents and Founder Ambition

Garry Tan discusses how AI is rewriting the startup playbook and enabling tiny teams to build businesses at scale.

The playbook for building high talent density teams | Adam Ward, Head of Talent at Cursor

Adam Ward discusses building high-talent-density teams and a three-step hiring framework.

9 Aug91 min listen/watch

ShopTalk Show

726: Be More Weird, Sameness is Ok, and People Noticing the Effort You Put In

Being a weirdo is something to aspire to in web creativity, as people notice the effort put into unique online work.

3 Aug53 min listen/watch

This CPO regrets that product management exists | Tom Verrilli (CPO of Whatnot)

Whatnot's CPO, Tom Verrilli, discusses his company's founding premise that product management's existence is regrettable, how AI is reshaping the PM role, and what he seeks in new hires.

2 Aug85 min listen/watch

Ruby Thelot on Internet Culture, AI, and the Future of Taste

Ruby Thelot discusses internet culture, AI, and digital communities, exploring how technology reshapes human relationships and creativity.

2 Aug34 min listen/watch

26 Jul33 min listen/watch

Ben Horowitz: The Fight Over Open Source AI

Ben Horowitz argues open source AI is crucial for security, innovation, and competition, countering efforts to restrict open models and prevent AI ecosystem dominance by a few labs.

26 Jul94 min listen/watch

Anthropic’s first technical PM on token maxing, the jagged edge, and living in the future | Dianne Penn

Anthropic's first technical product manager, Dianne Penn, discusses the company's rapid growth, the development of Claude's coding abilities, and the role of human judgment in AI.

22 Jul92 min listen/watch

Travis Kalanick Is Back | Building the Future of Industrial AI

Travis Kalanick discusses his vision for industrial AI and digitizing the physical world.

21 Jul81 min listen/watch

Why Physical AI Is the Next Frontier | Applied Intuition

Applied Intuition cofounders discuss the emergence of physical AI and their new Dana platform, designed to accelerate the development of autonomous systems and overcome deployment challenges.

19 Jul72 min listen/watch

Netflix CPTO on AI and the future of product and tech roles | Elizabeth Stone

Netflix CPTO Elizabeth Stone discusses the importance of systems thinking and AI fluency in product and tech roles.

12 Jul96 min listen/watch

How tech workers actually feel about AI in 2026 | Annual AI sentiment survey (Noam Segal)

A survey of thousands of tech workers reveals AI has split the workforce, with half thriving and half shaken, while burnout and job dissatisfaction surge.

22 Jun66 min listen/watch

Jake Paul & Anti Fund: From Creator to Investor

Jake Paul and Geoff Woo announce Anti Fund's $100 million growth fund and discuss their investment strategy and portfolio.

12 Jun28 min listen/watch

Samo Burja on Growth, Energy, and AI

AI's significant demand for compute, energy, and infrastructure could initiate a new wave of industrial expansion, impacting sectors far beyond just technology.

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